Novel nephron organoids that can be fine-tuned to represent the proximal convoluted tubule or loop of Henle have been ...
Arteriovenous fistula (AVF) stenosis is a complex pathological process caused by venous intimal hyperplasia, and its development is influenced by factors such as surgical injury, hemodynamic changes, ...
Look inside a brain cell with Huntington’s disease or ALS and you are likely to find RNA clumped together. These solid-like clusters, thought to be irreversible, can act as sponges that soak up ...
RNA clusters (green colored) gradually disassemble within biomolecular condensates (magenta colored), returning the RNA to a soluble state. This occured after an antisense oligonucleotide engineered ...
Summary: Circular RNAs (circRNAs) are stable, ring-shaped molecules that play crucial roles in brain development, cognition, and long-term cellular regulation. Unlike typical RNA, they form closed ...
The question of how life could have emerged is one of the most long-standing mysteries in science. In a new study, the laboratory of LMU Professor Dieter Braun has uncovered an unexpected form of ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The three-dimensional (3D) chromatin structure ...
Iron responsive element (IREs) mRNA and iron regulatory proteins (IRPs) regulate iron homeostasis. 5′-untranslated region motifs of APP IREs fold into RNA stem loops bind to IRP to control translation ...
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