The re-transcribed DNA is then integrated into the genome of the host cell (Figure 2). This process requires the absence of the nuclear membrane and thus is restricted to the M-phase of proliferating ...
Medical Xpress on MSN
HIV Integrase’s Shape-Shifting Role Offers Fresh Drug Targets
Salk Institute researchers determine the structure of HIV protein during a newly discovered function, enabling the ...
A reduction of the retrotransposon at the Drosophila NMJ leads to a drastic increase in synaptogenesis and plasticity (-copia). The structure of Copia (center), shows a large retroviral like structure ...
Viruses are entirely dependent on their hosts to reproduce. They ransack living cells for parts and energy and hijack the host's cellular machinery to make new copies of themselves. Herpes simplex ...
Genetic variants that cause rare disorders may remain elusive even after expansive testing, such as exome sequencing. The diagnostic yield of genome sequencing, particularly after a negative ...
Ancient invaders in the human genome play a fundamental role in development, as well as the regeneration of tissue. These invaders, called retrotransposons, “are ancient genetic elements that have ...
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