Substantial molecular evidence suggests a role for human papillomavirus (HPV) in the pathogenesis of oropharyngeal squamous-cell carcinoma, but epidemiologic data have been inconsistent. A high ...

One of the most common study designs used to assess pharmacogenetic effects is that of the case-control association study. In the context of pharmacogenetics, the usual approach is to examine the ...

Like cohort studies, the purpose of case-control studies is to establish association between exposure to risk factors and disease. Unlike cohort studies, however, members of the population with the ...

Whereas cardiovascular disease-related mortality has declined in most developed countries, its known prevalence is increasing worldwide, although few data on the causes of heart disease in the ...

In a nationally representative sample of 1.1 million homes, we compared the prevalence of smoking among 33,000 deceased women and 41,000 deceased men (case subjects) with the prevalence of smoking ...